From thousands of years ago, humankind is using natural products, diverse types of phytochemicals, food, drugs, hallucinogens along with microbial goods of bacteria, fungi, algae, and other available organisms in a difference of applications. Natural goods usually display a new process of the achievement and show novel therapeutic activities with considerable eventuality than that of synthetic compounds. These have been evidenced to help as hopeful sources of chemotherapy particularly in the case of cancer due to their new bioactive compounds with essential complexity and biological activeness (Verdine 1996). As a consequence of the many benefits, these innovative bioactive compounds gracious over synthetic replacements, and their isolation from natural resource on large scale is on the swing. In the current development, a massive work has been carried out in the field of mycology for extraction of bioactive compounds for commercial purposes. Fungi cell wall are rigid and contain complex polysaccharides called chitin and also having cytoplasmic membrane contain steroids (sterols). There is a vast variety of fungi be living on the earth, and some of them have a contribution in therapeutic use against pathogenic organisms; therefore, the endophytic fungi suited the center of attraction for investigators (Dias et al. 2012; Golinska et al. 2015).